Chemotherapy and the Immune Response in Protozoal Infections
Identifieur interne : 003797 ( Main/Exploration ); précédent : 003796; suivant : 003798Chemotherapy and the Immune Response in Protozoal Infections
Auteurs : William L. Hanson [États-Unis]Source :
- The Journal of Protozoology [ 0022-3921 ] ; 1981-02.
English descriptors
- Teeft :
- Amphotericin, Annual meeting, Antiprotozoal, Antiprotozoal drugs, Available evidence, Certain types, Chemotherapeutic agents, Chemotherapy, Complete adjuvant, Control mice, Cruzi, Cutaneous leishmaniasis, Georgetown university, Glucan, Guinea pigs, Human beings, Human lymphocytes, Immune, Immune mechanisms, Immune response, Immunoenhancing agents, Immunol, Infection, Lower numbers, Lymphocyte, Muramyl dipeptide, Nifurtimox, Parasite, Personal communication, Pokeweed mitogen, Polyamines, Protozoal, Protozoal diseases, Protozoal infections, Protozoan infections, Protozoan parasites, Such infections, Therapeutic concentrations, Trypanosoma cruzi, Various antiprotozoal drugs, Zoal infections.
Abstract
Available evidence indicates that many of the antiprotozoal drugs currently in use significantly modify the immune response of the host. The effect depends on both the drug and the host. Some drugs enhance the immune response, some are immuno‐suppressants, and others enhance some types of immune mechanisms while suppressing others. Future efforts in the development of antiprotozoal drugs should consider their effects on both the parasite and the immune response of the host. Also in the chemotherapy of protozoal infections consideration should be given to the combined usage of immunoenhancing agents and antiprotozoal drugs.
Url:
DOI: 10.1111/j.1550-7408.1981.tb02799.x
Affiliations:
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Le document en format XML
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